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POST GLP-1 TREATMENT:

What To do After your GLP-1 Treatment

24 hours after:

  • Avoid Heat and Sweat: This includes direct sunlight, strenuous exercise, steam rooms, saunas, and hot showers.

  • Hygiene: Maintain the treated area in a clean condition. Refrain from applying makeup or any products that may cause irritation.

  • Clothing: Avoid wearing tight or restrictive garments over the treated area, such as compression leggings, bodysuits, leotards, or similar clothing that may cause friction or occlusion.

1 - 4 days after:

  • Sun Exposure: Avoid direct sunlight and the use of tanning beds. Apply a broad-spectrum sunscreen with SPF 50 or higher daily. When outdoors, utilize physical protection such as wide-brimmed hats, large sunglasses, and breathable, protective clothing.

  • Topical Products: Refrain from applying products that may cause irritation to the treated area. This includes harsh soaps, exfoliating scrubs, medicated washes, retinoids, fragranced lotions, essential oils, and chemical peels.

  • Bathing and Water Exposure: Avoid hot showers, baths, saunas, and swimming pools of any temperature. When cleansing the area, use cool or lukewarm water with a mild, non-irritating cleanser. Gently pat the skin dry with a clean, soft towel—do not rub.

  • Mechanical Irritation: Do not scratch, scrub, or shave the treated area until fully healed.

  • Moisturization: To minimize irritation or pruritus, apply 1% hydrocortisone cream mixed with Vaseline® or Aquaphor® up to three times daily, or as directed by your provider.

  • Avoid Alcohol-Based Products: Skincare or cosmetics with alcohol can dry and irritate the skin. Stick to alcohol-free options.
Between Your Appointments

  • Sun Protection Is a Must (Minimum 2 Weeks): Limit sun exposure and apply SPF 50+ broad-spectrum sunscreen daily. Reapply every 2 hours when outdoors.

  • Exfoliation: If you shaved the area before your treatment, once redness and sensitivity subside (usually after 3 days), begin gentle exfoliation 2–3 times per week using a soft washcloth, exfoliating mitt, or mild scrub with fine particles, and optionally a light AHA/BHA product such as lactic acid or salicylic acid if your skin is not irritated to avoid ingrown hair. 

  • Moisturization: To minimize irritation or pruritus, apply 1% hydrocortisone cream mixed with Vaseline® or Aquaphor® up to three times daily, or as directed by your provider.

  • For Sensitive or Dry Skin: Introduce serums with niacinamide, hyaluronic acid, glycerin or peptides to help strengthen the skin barrier and support healing.
  • For Pigmentation Concerns: Starting 5-7 days after treatment, use brightening ingredients like Vitamin C, retinoids, kojic acid, azelaic acid, or tranexamic acid. Discontinue use 5 days before your next session to avoid sensitivity.
  • Don’t Pick or Rub: If you notice flaking or light scabbing (common with spot or texturizing treatments), let it heal naturally. Picking can cause irritation, scarring, or pigmentation.
  • Don’t Pick Pimples: Some mild breakouts may occur due to increased cell turnover. Let them resolve naturally to avoid post-inflammatory hyperpigmentation.

What to Except after GLP-1 Injections

GLP-1 medications (such as Semaglutide or Tirzepatide) work by mimicking a natural hormone in your body that helps regulate appetite, digestion, and blood sugar. They signal your brain to feel full sooner and stay full longer, which reduces hunger and makes it easier to eat smaller portions.

They also slow stomach emptying, helping control cravings and stabilize blood sugar. Over time, this leads to steady, healthy weight loss and improved metabolic health when paired with healthy habits.

Right After Treatment

  • Redness: Possible redness around injection site
  • Swelling: Swelling around the injection site.

    • first 2 weeks after

  • First Few Days/Week: The most common gastrointestinal side effects (nausea, vomiting, diarrhea, constipation, abdominal pain) often start very quickly, sometimes within a day or two of the first injection.
  • Dose Increase: Side effects may intensify temporarily when your healthcare provider increases the dosage, which is part of the standard treatment plan to help your body adapt gradually.

    • Between 2-4 weeks

  • Side Effects subside: Most Gastrointestinal side effect starts to fade
  • Reduced Appetite: Desire for food consumption decreases. 

    • Between 4-8 weeks

  • Stabilization: For most people, these initial side effects are mild to moderate and tend to decrease or resolve within the first 4 to 8 weeks of consistent use at a stable dose. 
  • Cravings: Especially for high-calorie or sugary foods—often become easier to manage.
  • Results: You should see noticeable weight loss at this point
  • Follow Up: Follow up with your provider every 3 months if there is no side effect. 
    • Results after your each treatment
    • Weight loss typically becomes more consistent as your dose stabilizes.
    • You may see improvements in: 
    1. Blood sugar control 
    2. Cholesterol levels 
    3. Blood pressure
    • Daily tasks, movement, and activity may begin to feel easier.

    When to Contact a Doctor

    While most side effects are manageable, some symptoms require immediate medical attention. Contact your healthcare provider if you experience:
    • Severe or persistent abdominal pain (which could indicate pancreatitis)
    • Persistent vomiting or diarrhea that leads to signs of dehydration (dizziness, dark urine, confusion)
    • Symptoms of a severe allergic reaction, such as difficulty breathing, swelling of the face or throat, or a spreading rash
    • Vision changes or eye pain 
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